Synthetic Peptide for Sleep Architecture Research
Technical Overview
DSIP 5mg is a synthetic peptide compound developed for laboratory research involving delta-wave EEG activity and hypothalamic-pituitary signaling, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying NMDA-receptor-associated neuromodulation, hypothalamic-pituitary-adrenal axis dynamics, and related biochemical mechanisms.
Delta Sleep-Inducing Peptide (DSIP) is a nonapeptide originally isolated from cerebral venous blood of sleeping rabbits. Its sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu has been shown to modulate delta-wave EEG activity and to interact with NMDA-receptor pathways, though its endogenous precursor remains uncharacterized.
Researchers use DSIP in rodent EEG studies, neuroendocrine-stress models, and comparative neuropeptide pharmacology. It is also investigated as a tool for probing the relationship between sleep architecture, circadian neuroendocrine output, and stress-response signaling.
This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.
Specifications
Compound Name: DSIP
Strength: 5mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.
Notice
Provided as a reference material for scientific investigation only.
Purity
≥99% by HPLC · COA available
CAS Number
62568-57-4
Molecular Formula
C35H48N10O15
Molecular Weight
848.81
Amino Acid Count
9
Sequence
Nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) with free N- and C-termini; originally isolated from cerebral venous blood of sleeping rabbits (full sequence per COA).
Physical Form
Lyophilized powder
Solubility
Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations.
Storage
Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol.
